Cargando…
Progressive mitochondrial protein lysine acetylation and heart failure in a model of Friedreich’s ataxia cardiomyopathy
INTRODUCTION: The childhood heart disease of Friedreich’s Ataxia (FRDA) is characterized by hypertrophy and failure. It is caused by loss of frataxin (FXN), a mitochondrial protein involved in energy homeostasis. FRDA model hearts have increased mitochondrial protein acetylation and impaired sirtuin...
Autores principales: | Stram, Amanda R., Wagner, Gregory R., Fogler, Brian D., Pride, P. Melanie, Hirschey, Matthew D., Payne, R. Mark |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444842/ https://www.ncbi.nlm.nih.gov/pubmed/28542596 http://dx.doi.org/10.1371/journal.pone.0178354 |
Ejemplares similares
-
The Pathogenesis of Cardiomyopathy in Friedreich Ataxia
por: Koeppen, Arnulf H., et al.
Publicado: (2015) -
Cardiomyopathy as the first manifestation of Friedreich's ataxia
por: Maffei, Rafael Tuzino Leite Neves, et al.
Publicado: (2020) -
Hepatic mitochondrial dysfunction in Friedreich Ataxia
por: Stüwe, Sven H, et al.
Publicado: (2011) -
Cardiovascular Research in Friedreich Ataxia: Unmet Needs and Opportunities
por: Payne, R. Mark
Publicado: (2022) -
Friedreich's Ataxia
por: Anderson, J. Wallace
Publicado: (1893)