Translation of Cardiac Myosin Activation With 2-Deoxy-ATP to Treat Heart Failure Via an Experimental Ribonucleotide Reductase-Based Gene Therapy

Despite recent advances, chronic heart failure remains a significant and growing unmet medical need, reaching epidemic proportions carrying substantial morbidity, mortality, and costs. A safe and convenient therapeutic agent that produces sustained inotropic effects could ameliorate symptoms and imp...

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Detalles Bibliográficos
Autores principales: Thomson, Kassandra S., Odom, Guy L., Murry, Charles E., Mahairas, Gregory G., Moussavi-Harami, Farid, Teichman, Sam L., Chen, Xiaolan, Hauschka, Stephen D., Chamberlain, Jeffrey S., Regnier, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
TRANSLATIONAL PERSPECTIVE
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444879/
https://www.ncbi.nlm.nih.gov/pubmed/28553667
http://dx.doi.org/10.1016/j.jacbts.2016.07.006

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