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Intramyocellular lipid excess in the mitochondrial disorder MELAS: MRS determination at 7T
OBJECTIVE: There is a paucity of objective, quantifiable indicators of mitochondrial disease available for clinical and scientific investigation. METHODS: To this end, we explore intramyocellular lipid (IMCL) accumulation noninvasively by 7T magnetic resonance spectroscopy (MRS) as a reporter of met...
Autores principales: | Golla, Sailaja, Ren, Jimin, Malloy, Craig R., Pascual, Juan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444911/ https://www.ncbi.nlm.nih.gov/pubmed/28589178 http://dx.doi.org/10.1212/NXG.0000000000000160 |
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