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Intramyocellular lipid excess in the mitochondrial disorder MELAS: MRS determination at 7T

OBJECTIVE: There is a paucity of objective, quantifiable indicators of mitochondrial disease available for clinical and scientific investigation. METHODS: To this end, we explore intramyocellular lipid (IMCL) accumulation noninvasively by 7T magnetic resonance spectroscopy (MRS) as a reporter of met...

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Detalles Bibliográficos
Autores principales: Golla, Sailaja, Ren, Jimin, Malloy, Craig R., Pascual, Juan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444911/
https://www.ncbi.nlm.nih.gov/pubmed/28589178
http://dx.doi.org/10.1212/NXG.0000000000000160

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