Mosaic chromosome Y loss and testicular germ cell tumor risk

Studies have suggested mosaic loss of chromosome Y (mLOY) in blood-derived DNA is common in older men. Cohort studies investigating mLOY and mortality have reported contradictory results. Previous work found a 1.6 Mb deletion of the AZFc region on the Y chromosome (the “gr/gr” deletion) is associate...

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Detalles Bibliográficos
Autores principales: Machiela, Mitchell J., Dagnall, Casey L., Pathak, Anand, Loud, Jennifer T., Chanock, Stephen J., Greene, Mark H., McGlynn, Katherine A., Stewart, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444985/
https://www.ncbi.nlm.nih.gov/pubmed/28275244
http://dx.doi.org/10.1038/jhg.2017.20

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