Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation

The NLRP3 inflammasome is activated in the early period following subarachnoid hemorrhage(SAH), resulting in inflammatory responses. Recent studies have shown that activation of NLRP3 inflammasome is suppressed by autophagy, but the potential mechanism is unclear. In this study, we examined whether...

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Detalles Bibliográficos
Autores principales: Cao, Shenglong, Shrestha, Sudeep, Li, Jianru, Yu, Xiaobo, Chen, Jingyin, Yan, Feng, Ying, Guangyu, Gu, Chi, Wang, Lin, Chen, Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445068/
https://www.ncbi.nlm.nih.gov/pubmed/28546552
http://dx.doi.org/10.1038/s41598-017-02679-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445068/
https://www.ncbi.nlm.nih.gov/pubmed/28546552
http://dx.doi.org/10.1038/s41598-017-02679-z

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