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Intratumoral FoxP3(+)Helios(+) Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer
Regulatory T cells (Tregs) can be antitumorigenic or pro-tumorigenic in colorectal cancer (CRC) depending on the presence of different Treg subsets with various immunosuppressive molecules. Some studies reported the phenotypic characteristics of tumor-infiltrating immune cells in CRC, but limited st...
Autores principales: | Syed Khaja, Azharuddin Sajid, Toor, Salman M., El Salhat, Haytham, Ali, Bassam R., Elkord, Eyad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445103/ https://www.ncbi.nlm.nih.gov/pubmed/28603527 http://dx.doi.org/10.3389/fimmu.2017.00619 |
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