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Comparison of Sirtuin 3 Levels in ALS and Huntington’s Disease—Differential Effects in Human Tissue Samples vs. Transgenic Mouse Models

Neurodegenerative diseases are characterized by distinct patterns of neuronal loss. In amyotrophic lateral sclerosis (ALS) upper and lower motoneurons degenerate whereas in Huntington’s disease (HD) medium spiny neurons in the striatum are preferentially affected. Despite these differences the patho...

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Detalles Bibliográficos
Autores principales:	Buck, Eva, Bayer, Hanna, Lindenberg, Katrin S., Hanselmann, Johannes, Pasquarelli, Noemi, Ludolph, Albert C., Weydt, Patrick, Witting, Anke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445120/ https://www.ncbi.nlm.nih.gov/pubmed/28603486 http://dx.doi.org/10.3389/fnmol.2017.00156

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