Population Pharmacokinetics of Morphine in Patients With Nonalcoholic Steatohepatitis (NASH) and Healthy Adults

Altered expression and function of transporters in nonalcoholic steatohepatitis (NASH) patients may affect the pharmacokinetics (PK), efficacy, and safety of substrate drugs. A population pharmacokinetic (PopPK) analysis was performed to assess differences in morphine and morphine‐3‐glucuronide (M3G...

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Detalles Bibliográficos
Autores principales: Pierre, V, Johnston, CK, Ferslew, BC, Brouwer, KLR, Gonzalez, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445229/
https://www.ncbi.nlm.nih.gov/pubmed/28417561
http://dx.doi.org/10.1002/psp4.12185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445229/
https://www.ncbi.nlm.nih.gov/pubmed/28417561
http://dx.doi.org/10.1002/psp4.12185

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