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Direct reprogramming of fibroblasts into cardiomyocytes

Cardiovascular diseases are the leading causes of death in the world. The limited regenerative capacity of adult cardiomyocytes is the major barrier for heart regeneration. After myocardial infarction, myofibroblasts are the dominant cell type in the infarct zone. Therefore, it is a good idea to rep...

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Detalles Bibliográficos
Autores principales: Chen, Yueqiu, Yang, Ziying, Zhao, Zhen-Ao, Shen, Zhenya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445304/
https://www.ncbi.nlm.nih.gov/pubmed/28545505
http://dx.doi.org/10.1186/s13287-017-0569-3