Roles of LncRNAs in Viral Infections

Many proteins and signaling pathways participate in anti-viral host responses. Long non-coding RNAs (lncRNAs), a subset of non-coding RNAs greater than 200 nucleotides in length, have been recently described as critical regulators in viral infections. Accumulating research indicates that lncRNAs are...

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Detalles Bibliográficos
Autores principales: Liu, Weiwei, Ding, Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445353/
https://www.ncbi.nlm.nih.gov/pubmed/28603696
http://dx.doi.org/10.3389/fcimb.2017.00205
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author Liu, Weiwei
Ding, Chan
author_facet Liu, Weiwei
Ding, Chan
author_sort Liu, Weiwei
collection PubMed
description Many proteins and signaling pathways participate in anti-viral host responses. Long non-coding RNAs (lncRNAs), a subset of non-coding RNAs greater than 200 nucleotides in length, have been recently described as critical regulators in viral infections. Accumulating research indicates that lncRNAs are important in the development and progression of infectious diseases. LncRNAs are not only involved in anti-viral responses, but in many different virus-host interactions, some of which may be beneficial to the virus. Here we review the current knowledge regarding host and viral lncRNAs and their roles in viral infections. In addition, the potential of using lncRNAs as diagnostic biomarkers is discussed.
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spelling pubmed-54453532017-06-09 Roles of LncRNAs in Viral Infections Liu, Weiwei Ding, Chan Front Cell Infect Microbiol Microbiology Many proteins and signaling pathways participate in anti-viral host responses. Long non-coding RNAs (lncRNAs), a subset of non-coding RNAs greater than 200 nucleotides in length, have been recently described as critical regulators in viral infections. Accumulating research indicates that lncRNAs are important in the development and progression of infectious diseases. LncRNAs are not only involved in anti-viral responses, but in many different virus-host interactions, some of which may be beneficial to the virus. Here we review the current knowledge regarding host and viral lncRNAs and their roles in viral infections. In addition, the potential of using lncRNAs as diagnostic biomarkers is discussed. Frontiers Media S.A. 2017-05-26 /pmc/articles/PMC5445353/ /pubmed/28603696 http://dx.doi.org/10.3389/fcimb.2017.00205 Text en Copyright © 2017 Liu and Ding. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Liu, Weiwei
Ding, Chan
Roles of LncRNAs in Viral Infections
title Roles of LncRNAs in Viral Infections
title_full Roles of LncRNAs in Viral Infections
title_fullStr Roles of LncRNAs in Viral Infections
title_full_unstemmed Roles of LncRNAs in Viral Infections
title_short Roles of LncRNAs in Viral Infections
title_sort roles of lncrnas in viral infections
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445353/
https://www.ncbi.nlm.nih.gov/pubmed/28603696
http://dx.doi.org/10.3389/fcimb.2017.00205
work_keys_str_mv AT liuweiwei rolesoflncrnasinviralinfections
AT dingchan rolesoflncrnasinviralinfections

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