Cargando…

The observation during small incision lenticule extraction for myopia with corneal opacity

BACKGROUND: To evaluate the feasibility and efficacy of small incision lenticule extraction (SMILE) in the treatment of myopia with corneal opacity. METHODS: To evaluate the treatment of myopia with corneal opacity, 9 patients (4 males, 5 females) who underwent SMILE were enrolled in this prospectiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Shaowei, Xu, Haipeng, Zheng, Ke, Zhao, Jing, Jian, Weijun, Li, Meiyan, Zhou, Xingtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445429/
https://www.ncbi.nlm.nih.gov/pubmed/28545414
http://dx.doi.org/10.1186/s12886-017-0474-7
_version_ 1783238888212398080
author Zhang, Shaowei
Xu, Haipeng
Zheng, Ke
Zhao, Jing
Jian, Weijun
Li, Meiyan
Zhou, Xingtao
author_facet Zhang, Shaowei
Xu, Haipeng
Zheng, Ke
Zhao, Jing
Jian, Weijun
Li, Meiyan
Zhou, Xingtao
author_sort Zhang, Shaowei
collection PubMed
description BACKGROUND: To evaluate the feasibility and efficacy of small incision lenticule extraction (SMILE) in the treatment of myopia with corneal opacity. METHODS: To evaluate the treatment of myopia with corneal opacity, 9 patients (4 males, 5 females) who underwent SMILE were enrolled in this prospective clinical study. One eye of each patient was treated. The results of laser scanning and lenticule extraction were observed during the surgery, and the surgical videos were again reviewed after surgery. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and spherical equivalence (SE) were noted at 1 month after surgery. The depth and density of the corneal opacities were measured by anterior segment optical coherence tomography (AS-OCT) and the Pentacam anterior eye segment analyzer. RESULTS: All procedures were uneventful and no intraoperative complications were observed. At 1 month after surgery, the UDVA of all patients was 20/25 or better and no patients lost Snellen lines. The mean safety and efficacy indexes were 1.10 ± 0.24 and 1.08 ± 0.16, respectively, at 1 month postoperatively. The mean postoperative spherical equivalent was 0.27 ± 0.23 diopter (D). All eyes were within ±0.75 D and 8 eyes (88.9%) were within ±0.50 D. There was no eccentric corneal topography or abnormal morphology in the corneal caps. The corneal opacities of all patients were within the optical zone. The mean preoperative depths in the deepest areas of corneal opacity were 152 ± 38 μm (range: 86–217 μm); at 1 month after surgery (P < .01), they were 117 ± 28 μm (range: 86–189 μm). The preoperative maximum density of corneal opacity was 48.5 ± 20.7 (range: 20.4 to 85.8); at 1 month after surgery (P > .05), it was 49.8 ± 26.7 (range: 19.8 to 82.5) at 1 month after surgery. CONCLUSION: Patients with corneal opacity can be successfully treated with the SMILE operation. The short-term outcome was good, however the long-term results need further study. TRIAL REGISTRATION: The trial registration number: ChiCTR-ONRC-13003114, Date of Last Refreshed on: 2016-01-27, Date of registration on 2013-03-17(retrospectively registered).
format Online
Article
Text
id pubmed-5445429
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-54454292017-05-30 The observation during small incision lenticule extraction for myopia with corneal opacity Zhang, Shaowei Xu, Haipeng Zheng, Ke Zhao, Jing Jian, Weijun Li, Meiyan Zhou, Xingtao BMC Ophthalmol Research Article BACKGROUND: To evaluate the feasibility and efficacy of small incision lenticule extraction (SMILE) in the treatment of myopia with corneal opacity. METHODS: To evaluate the treatment of myopia with corneal opacity, 9 patients (4 males, 5 females) who underwent SMILE were enrolled in this prospective clinical study. One eye of each patient was treated. The results of laser scanning and lenticule extraction were observed during the surgery, and the surgical videos were again reviewed after surgery. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and spherical equivalence (SE) were noted at 1 month after surgery. The depth and density of the corneal opacities were measured by anterior segment optical coherence tomography (AS-OCT) and the Pentacam anterior eye segment analyzer. RESULTS: All procedures were uneventful and no intraoperative complications were observed. At 1 month after surgery, the UDVA of all patients was 20/25 or better and no patients lost Snellen lines. The mean safety and efficacy indexes were 1.10 ± 0.24 and 1.08 ± 0.16, respectively, at 1 month postoperatively. The mean postoperative spherical equivalent was 0.27 ± 0.23 diopter (D). All eyes were within ±0.75 D and 8 eyes (88.9%) were within ±0.50 D. There was no eccentric corneal topography or abnormal morphology in the corneal caps. The corneal opacities of all patients were within the optical zone. The mean preoperative depths in the deepest areas of corneal opacity were 152 ± 38 μm (range: 86–217 μm); at 1 month after surgery (P < .01), they were 117 ± 28 μm (range: 86–189 μm). The preoperative maximum density of corneal opacity was 48.5 ± 20.7 (range: 20.4 to 85.8); at 1 month after surgery (P > .05), it was 49.8 ± 26.7 (range: 19.8 to 82.5) at 1 month after surgery. CONCLUSION: Patients with corneal opacity can be successfully treated with the SMILE operation. The short-term outcome was good, however the long-term results need further study. TRIAL REGISTRATION: The trial registration number: ChiCTR-ONRC-13003114, Date of Last Refreshed on: 2016-01-27, Date of registration on 2013-03-17(retrospectively registered). BioMed Central 2017-05-25 /pmc/articles/PMC5445429/ /pubmed/28545414 http://dx.doi.org/10.1186/s12886-017-0474-7 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Zhang, Shaowei
Xu, Haipeng
Zheng, Ke
Zhao, Jing
Jian, Weijun
Li, Meiyan
Zhou, Xingtao
The observation during small incision lenticule extraction for myopia with corneal opacity
title The observation during small incision lenticule extraction for myopia with corneal opacity
title_full The observation during small incision lenticule extraction for myopia with corneal opacity
title_fullStr The observation during small incision lenticule extraction for myopia with corneal opacity
title_full_unstemmed The observation during small incision lenticule extraction for myopia with corneal opacity
title_short The observation during small incision lenticule extraction for myopia with corneal opacity
title_sort observation during small incision lenticule extraction for myopia with corneal opacity
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445429/
https://www.ncbi.nlm.nih.gov/pubmed/28545414
http://dx.doi.org/10.1186/s12886-017-0474-7
work_keys_str_mv AT zhangshaowei theobservationduringsmallincisionlenticuleextractionformyopiawithcornealopacity
AT xuhaipeng theobservationduringsmallincisionlenticuleextractionformyopiawithcornealopacity
AT zhengke theobservationduringsmallincisionlenticuleextractionformyopiawithcornealopacity
AT zhaojing theobservationduringsmallincisionlenticuleextractionformyopiawithcornealopacity
AT jianweijun theobservationduringsmallincisionlenticuleextractionformyopiawithcornealopacity
AT limeiyan theobservationduringsmallincisionlenticuleextractionformyopiawithcornealopacity
AT zhouxingtao theobservationduringsmallincisionlenticuleextractionformyopiawithcornealopacity
AT zhangshaowei observationduringsmallincisionlenticuleextractionformyopiawithcornealopacity
AT xuhaipeng observationduringsmallincisionlenticuleextractionformyopiawithcornealopacity
AT zhengke observationduringsmallincisionlenticuleextractionformyopiawithcornealopacity
AT zhaojing observationduringsmallincisionlenticuleextractionformyopiawithcornealopacity
AT jianweijun observationduringsmallincisionlenticuleextractionformyopiawithcornealopacity
AT limeiyan observationduringsmallincisionlenticuleextractionformyopiawithcornealopacity
AT zhouxingtao observationduringsmallincisionlenticuleextractionformyopiawithcornealopacity