Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm

Despite rapid advancement in generation of large-scale microarray gene expression datasets, robust multigene expression signatures that are capable of guiding the use of specific therapies have not been routinely implemented into clinical care. We have developed an iterative resampling analysis to p...

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Detalles Bibliográficos
Autores principales: McGrail, Daniel J., Lin, Curtis Chun-Jen, Garnett, Jeannine, Liu, Qingxin, Mo, Wei, Dai, Hui, Lu, Yiling, Yu, Qinghua, Ju, Zhenlin, Yin, Jun, Vellano, Christopher P., Hennessy, Bryan, Mills, Gordon B., Lin, Shiaw-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445594/
https://www.ncbi.nlm.nih.gov/pubmed/28649435
http://dx.doi.org/10.1038/s41540-017-0011-6

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