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Functionally and morphologically damaged mitochondria observed in auditory cells under senescence-inducing stress

We aimed at determining the mitochondrial function in premature senescence model of auditory cells. Short exposure to H(2)O(2) (1 h, 0.1 mM) induced premature cellular senescence in House Ear Institute-Organ of Corti 1 auditory cells. The transmission electron microscopy analysis revealed that damag...

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Detalles Bibliográficos
Autores principales: Kamogashira, Teru, Hayashi, Ken, Fujimoto, Chisato, Iwasaki, Shinichi, Yamasoba, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445612/
https://www.ncbi.nlm.nih.gov/pubmed/28649420
http://dx.doi.org/10.1038/s41514-017-0002-2