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Calcium Orthophosphates in Nature, Biology and Medicine

The present overview is intended to point the readers’ attention to the important subject of calcium orthophosphates. These materials are of the special significance because they represent the inorganic part of major normal (bones, teeth and dear antlers) and pathological (i.e. those appearing due t...

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Autor principal: Dorozhkin, Sergey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445702/
http://dx.doi.org/10.3390/ma2020399
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author Dorozhkin, Sergey V.
author_facet Dorozhkin, Sergey V.
author_sort Dorozhkin, Sergey V.
collection PubMed
description The present overview is intended to point the readers’ attention to the important subject of calcium orthophosphates. These materials are of the special significance because they represent the inorganic part of major normal (bones, teeth and dear antlers) and pathological (i.e. those appearing due to various diseases) calcified tissues of mammals. Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium ortho-phosphates. For example, self-setting hydraulic cements made of calcium orthophosphates are helpful in bone repair, while titanium substitutes covered by a surface layer of calcium orthophosphates are used for hip joint endoprostheses and as tooth substitutes. Porous scaffolds made of calcium orthophosphates are very promising tools for tissue engineering applications. In addition, technical grade calcium orthophosphates are very popular mineral fertilizers. Thus ere calcium orthophosphates are of great significance for humankind and, in this paper, an overview on the current knowledge on this subject is provided.
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spelling pubmed-54457022017-07-28 Calcium Orthophosphates in Nature, Biology and Medicine Dorozhkin, Sergey V. Materials (Basel) Review The present overview is intended to point the readers’ attention to the important subject of calcium orthophosphates. These materials are of the special significance because they represent the inorganic part of major normal (bones, teeth and dear antlers) and pathological (i.e. those appearing due to various diseases) calcified tissues of mammals. Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium ortho-phosphates. For example, self-setting hydraulic cements made of calcium orthophosphates are helpful in bone repair, while titanium substitutes covered by a surface layer of calcium orthophosphates are used for hip joint endoprostheses and as tooth substitutes. Porous scaffolds made of calcium orthophosphates are very promising tools for tissue engineering applications. In addition, technical grade calcium orthophosphates are very popular mineral fertilizers. Thus ere calcium orthophosphates are of great significance for humankind and, in this paper, an overview on the current knowledge on this subject is provided. Molecular Diversity Preservation International 2009-04-20 /pmc/articles/PMC5445702/ http://dx.doi.org/10.3390/ma2020399 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Dorozhkin, Sergey V.
Calcium Orthophosphates in Nature, Biology and Medicine
title Calcium Orthophosphates in Nature, Biology and Medicine
title_full Calcium Orthophosphates in Nature, Biology and Medicine
title_fullStr Calcium Orthophosphates in Nature, Biology and Medicine
title_full_unstemmed Calcium Orthophosphates in Nature, Biology and Medicine
title_short Calcium Orthophosphates in Nature, Biology and Medicine
title_sort calcium orthophosphates in nature, biology and medicine
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445702/
http://dx.doi.org/10.3390/ma2020399
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