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Advances in Porous Biomaterials for Dental and Orthopaedic Applications
The connective hard tissues bone and teeth are highly porous on a micrometer scale, but show high values of compression strength at a relatively low weight. The fabrication of porous materials has been actively researched and different processes have been developed that vary in preparation complexit...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445918/ http://dx.doi.org/10.3390/ma3052947 |
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author | Mour, Meenakshi Das, Debarun Winkler, Thomas Hoenig, Elisa Mielke, Gabriela Morlock, Michael M. Schilling, Arndt F. |
author_facet | Mour, Meenakshi Das, Debarun Winkler, Thomas Hoenig, Elisa Mielke, Gabriela Morlock, Michael M. Schilling, Arndt F. |
author_sort | Mour, Meenakshi |
collection | PubMed |
description | The connective hard tissues bone and teeth are highly porous on a micrometer scale, but show high values of compression strength at a relatively low weight. The fabrication of porous materials has been actively researched and different processes have been developed that vary in preparation complexity and also in the type of porous material that they produce. Methodologies are available for determination of pore properties. The purpose of the paper is to give an overview of these methods, the role of porosity in natural porous materials and the effect of pore properties on the living tissues. The minimum pore size required to allow the ingrowth of mineralized tissue seems to be in the order of 50 µm: larger pore sizes seem to improve speed and depth of penetration of mineralized tissues into the biomaterial, but on the other hand impair the mechanical properties. The optimal pore size is therefore dependent on the application and the used material. |
format | Online Article Text |
id | pubmed-5445918 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-54459182017-07-28 Advances in Porous Biomaterials for Dental and Orthopaedic Applications Mour, Meenakshi Das, Debarun Winkler, Thomas Hoenig, Elisa Mielke, Gabriela Morlock, Michael M. Schilling, Arndt F. Materials (Basel) Review The connective hard tissues bone and teeth are highly porous on a micrometer scale, but show high values of compression strength at a relatively low weight. The fabrication of porous materials has been actively researched and different processes have been developed that vary in preparation complexity and also in the type of porous material that they produce. Methodologies are available for determination of pore properties. The purpose of the paper is to give an overview of these methods, the role of porosity in natural porous materials and the effect of pore properties on the living tissues. The minimum pore size required to allow the ingrowth of mineralized tissue seems to be in the order of 50 µm: larger pore sizes seem to improve speed and depth of penetration of mineralized tissues into the biomaterial, but on the other hand impair the mechanical properties. The optimal pore size is therefore dependent on the application and the used material. MDPI 2010-04-28 /pmc/articles/PMC5445918/ http://dx.doi.org/10.3390/ma3052947 Text en © 2010 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Mour, Meenakshi Das, Debarun Winkler, Thomas Hoenig, Elisa Mielke, Gabriela Morlock, Michael M. Schilling, Arndt F. Advances in Porous Biomaterials for Dental and Orthopaedic Applications |
title | Advances in Porous Biomaterials for Dental and Orthopaedic Applications |
title_full | Advances in Porous Biomaterials for Dental and Orthopaedic Applications |
title_fullStr | Advances in Porous Biomaterials for Dental and Orthopaedic Applications |
title_full_unstemmed | Advances in Porous Biomaterials for Dental and Orthopaedic Applications |
title_short | Advances in Porous Biomaterials for Dental and Orthopaedic Applications |
title_sort | advances in porous biomaterials for dental and orthopaedic applications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445918/ http://dx.doi.org/10.3390/ma3052947 |
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