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Association of gain-of-function EPHX2 polymorphism Lys55Arg with acute kidney injury following cardiac surgery

Twenty to thirty percent of patients undergoing cardiac surgery develop acute kidney injury (AKI). In mice, inhibition of soluble epoxide hydrolase (sEH) attenuates renal injury following ischemia-reperfusion. We tested the hypothesis that functional variants of EPHX2, encoding sEH, are associated w...

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Detalles Bibliográficos
Autores principales:	Shuey, Megan M., Billings, Frederic T., Wei, Shouzou, Milne, Ginger L., Nian, Hui, Yu, Chang, Brown, Nancy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446112/ https://www.ncbi.nlm.nih.gov/pubmed/28552948 http://dx.doi.org/10.1371/journal.pone.0175292

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