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Sex-specific effect of CPB2 Ala147Thr but not Thr325Ile variants on the risk of venous thrombosis: A comprehensive meta-analysis
BACKGROUND: Thrombin activatable fibrinolysis inhibitor (TAFI), encoded by the Carboxypeptidase B2 gene (CPB2), is an inhibitor of fibrinolysis and plays a role in the pathogenesis of venous thrombosis. Experimental findings support a functional role of genetic variants in CPB2, while epidemiologica...
Autores principales: | Zwingerman, Nora, Medina-Rivera, Alejandra, Kassam, Irfahan, Wilson, Michael D., Morange, Pierre-Emmanuel, Trégouët, David-Alexandre, Gagnon, France |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446132/ https://www.ncbi.nlm.nih.gov/pubmed/28552956 http://dx.doi.org/10.1371/journal.pone.0177768 |
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