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Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the “safe harbor” AAVS1 locus

We report the generation-characterization of a fetal liver (FL) B-cell progenitor (BCP)-derived human induced pluripotent stem cell (hiPSC) line CRISPR/Cas9-edited to carry/express a single copy of doxycycline-inducible Cas9 gene in the “safe locus” AAVS1 (iCas9-FL-BCP-hiPSC). Gene-edited iPSCs rema...

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Detalles Bibliográficos
Autores principales:	Castaño, Julio, Bueno, Clara, Jiménez-Delgado, Senda, Roca-Ho, Heleia, Fraga, Mario F., Fernandez, Agustín F., Nakanishi, Mahito, Torres-Ruiz, Raúl, Rodríguez-Perales, Sandra, Menéndez, Pablo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Lab Resource: Stem Cell Line
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446316/ https://www.ncbi.nlm.nih.gov/pubmed/28677529 http://dx.doi.org/10.1016/j.scr.2017.04.011

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