Differential methylation is associated with non-syndromic cleft lip and palate and contributes to penetrance effects

Non-syndromic cleft lip and/or palate (NSCLP) is a common congenital malformation with a multifactorial model of inheritance. Although several at-risk alleles have been identified, they do not completely explain the high heritability. We postulate that epigenetic factors as DNA methylation might con...

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Detalles Bibliográficos
Autores principales: Alvizi, Lucas, Ke, Xiayi, Brito, Luciano Abreu, Seselgyte, Rimante, Moore, Gudrun E., Stanier, Philip, Passos-Bueno, Maria Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446392/
https://www.ncbi.nlm.nih.gov/pubmed/28550290
http://dx.doi.org/10.1038/s41598-017-02721-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446392/
https://www.ncbi.nlm.nih.gov/pubmed/28550290
http://dx.doi.org/10.1038/s41598-017-02721-0

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