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Differential methylation is associated with non-syndromic cleft lip and palate and contributes to penetrance effects
Non-syndromic cleft lip and/or palate (NSCLP) is a common congenital malformation with a multifactorial model of inheritance. Although several at-risk alleles have been identified, they do not completely explain the high heritability. We postulate that epigenetic factors as DNA methylation might con...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446392/ https://www.ncbi.nlm.nih.gov/pubmed/28550290 http://dx.doi.org/10.1038/s41598-017-02721-0 |