A-to-I editing in human miRNAs is enriched in seed sequence, influenced by sequence contexts and significantly hypoedited in glioblastoma multiforme

Editing in microRNAs, particularly in seed can significantly alter the choice of their target genes. We show that out of 13 different human tissues, different regions of brain showed higher adenosine to inosine (A-to-I) editing in mature miRNAs. These events were enriched in seed sequence (73.33%),...

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Detalles Bibliográficos
Autores principales: Paul, Deepanjan, Sinha, Ashis Narayan, Ray, Arjun, Lal, Megha, Nayak, Subhashree, Sharma, Anchal, Mehani, Bharati, Mukherjee, Debasish, Laddha, Saurabh V., Suri, Ashish, Sarkar, Chitra, Mukhopadhyay, Arijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446428/
https://www.ncbi.nlm.nih.gov/pubmed/28550310
http://dx.doi.org/10.1038/s41598-017-02397-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446428/
https://www.ncbi.nlm.nih.gov/pubmed/28550310
http://dx.doi.org/10.1038/s41598-017-02397-6

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