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ANTITUMOR AND APOPTOTIC EFFECTS OF CUCURBITACIN A IN A-549 LUNG CARCINOMA CELLS IS MEDIATED VIA G2/M CELL CYCLE ARREST AND M-TOR/PI3K/AKT SIGNALLING PATHWAY

BACKGROUND: The main aim of this study was to demonstrate the antitumor potential of cucurbitacin A on A-549 NSCLC (non-small cell lung cancer cells). The effects of Cucurbitacin A on apoptotic induction, cell physic, cell cycle failure and m-TOR/PI3K/Akt signalling pathway were also investigated in...

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Detalles Bibliográficos
Autores principales:	Wang, Wen-dong, Liu, Yan, Su, Yuan, Xiong, Xian-zhi, Shang, Dan, Xu, Juan-juan, Liu, Hong-ju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	African Traditional Herbal Medicine Supporters Initiative (ATHMSI) 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446468/ https://www.ncbi.nlm.nih.gov/pubmed/28573224 http://dx.doi.org/10.21010/ajtcam.v14i2.9

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