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Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration

BACKGROUND: Penetration of the mammary gland basement membrane by cancer cells is a crucial first step in tumor invasion. Using a mouse model of ductal carcinoma in situ, we previously found that inhibition of peptidylarginine deiminase 2 (PAD2, aka PADI2) activity appears to maintain basement membr...

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Detalles Bibliográficos
Autores principales:	Horibata, Sachi, Rogers, Katherine E., Sadegh, David, Anguish, Lynne J., McElwee, John L., Shah, Pragya, Thompson, Paul R., Coonrod, Scott A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446677/ https://www.ncbi.nlm.nih.gov/pubmed/28549415 http://dx.doi.org/10.1186/s12885-017-3354-x

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