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Late onset Alzheimer’s disease genetics implicates microglial pathways in disease risk

Alzheimer’s disease (AD) is a highly heritable complex disease with no current effective prevention or treatment. The majority of drugs developed for AD focus on the amyloid cascade hypothesis, which implicates Aß plaques as a causal factor in the disease. However, it is possible that other underexp...

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Detalles Bibliográficos
Autores principales:	Efthymiou, Anastasia G., Goate, Alison M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446752/ https://www.ncbi.nlm.nih.gov/pubmed/28549481 http://dx.doi.org/10.1186/s13024-017-0184-x

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