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Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype
BACKGROUND: Genetic studies for complex diseases have predominantly discovered main effects at individual loci, but have not focused on genomic and environmental contexts important for a phenotype. Gene Set Enrichment Analysis (GSEA) aims to address this by identifying sets of genes or biological pa...
Autores principales: | Tragante, Vinicius, Gho, Johannes M. I. H., Felix, Janine F., Vasan, Ramachandran S., Smith, Nicholas L., Voight, Benjamin F., Palmer, Colin, van der Harst, Pim, Moore, Jason H., Asselbergs, Folkert W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446754/ https://www.ncbi.nlm.nih.gov/pubmed/28559929 http://dx.doi.org/10.1186/s13040-017-0137-5 |
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