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Fluorescent CXCR4 targeting peptide as alternative for antibody staining in Ewing sarcoma

BACKGROUND: Ewing sarcoma is an aggressive, highly metastatic primary bone and soft tissue tumor most frequently occurring in the bone of young adolescents. Patients, especially those diagnosed with a metastatic disease, have a poor overall survival. Chemokine receptor CXCR4 has a key pro-tumorigeni...

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Detalles Bibliográficos
Autores principales: Sand, Laurens G. L., Buckle, Tessa, van Leeuwen, Fijs W. B., Corver, Willem E., Kruisselbrink, Alwine B., Jochemsen, Aart G., Hogendoorn, Pancras C. W., Szuhai, Károly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446759/
https://www.ncbi.nlm.nih.gov/pubmed/28549419
http://dx.doi.org/10.1186/s12885-017-3352-z