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Interactions of 172 plant extracts with human organic anion transporter 1 (SLC22A6) and 3 (SLC22A8): a study on herb-drug interactions

BACKGROUND: Herb-drug interactions (HDIs) resulting from concomitant use of herbal products with clinical drugs may cause adverse reactions. Organic anion transporter 1 (OAT1) and 3 (OAT3) are highly expressed in the kidney and play a key role in the renal elimination of substrate drugs. So far, lit...

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Detalles Bibliográficos
Autores principales: Lu, Hang, Lu, Zhiqiang, Li, Xue, Li, Gentao, Qiao, Yilin, Borris, Robert P., Zhang, Youcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446775/
https://www.ncbi.nlm.nih.gov/pubmed/28560096
http://dx.doi.org/10.7717/peerj.3333