Overexpression of Mineralocorticoid Receptors in the Mouse Forebrain Partly Alleviates the Effects of Chronic Early Life Stress on Spatial Memory, Neurogenesis and Synaptic Function in the Dentate Gyrus

Evidence from human studies suggests that high expression of brain mineralocorticoid receptors (MR) may promote resilience against negative consequences of stress exposure, including childhood trauma. We examined, in mice, whether brain MR overexpression can alleviate the effects of chronic early li...

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Detalles Bibliográficos
Autores principales: Kanatsou, Sofia, Karst, Henk, Kortesidou, Despoina, van den Akker, Rachelle A., den Blaauwen, Jan, Harris, Anjanette P., Seckl, Jonathan R., Krugers, Harm J., Joels, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447008/
https://www.ncbi.nlm.nih.gov/pubmed/28611594
http://dx.doi.org/10.3389/fncel.2017.00132

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