Genetic Variability as a Regulator of TLR4 and NOD Signaling in Response to Bacterial Driven DNA Damage Response (DDR) and Inflammation: Focus on the Gastrointestinal (GI) Tract

The fundamental role of human Toll-like receptors (TLRs) and NOD-like receptors (NLRs), the two most studied pathogen recognition receptors (PRRs), is the protection against pathogens and excessive tissue injury. Recent evidence supports the association between TLR/NLR gene mutations and susceptibil...

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Detalles Bibliográficos
Autores principales: Spanou, Evagelia, Kalisperati, Polyxeni, Pateras, Ioannis S., Papalampros, Alexandros, Barbouti, Alexandra, Tzioufas, Athanasios G., Kotsinas, Athanassios, Sougioultzis, Stavros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447025/
https://www.ncbi.nlm.nih.gov/pubmed/28611823
http://dx.doi.org/10.3389/fgene.2017.00065

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