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Mineralocorticoid Receptor Signaling as a Therapeutic Target for Renal and Cardiac Fibrosis

Activation of the mineralocorticoid receptor (MR) plays important roles in both physiological and pathological events. Blockade of MR signaling with MR antagonists (MRAs) has been used clinically to treat kidney and cardiac disease associated with hypertension and other chronic diseases, resulting i...

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Detalles Bibliográficos
Autores principales: Tesch, Greg H., Young, Morag J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447060/
https://www.ncbi.nlm.nih.gov/pubmed/28611666
http://dx.doi.org/10.3389/fphar.2017.00313