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admixturegraph: an R package for admixture graph manipulation and fitting

SUMMARY: Admixture graphs generalize phylogenetic trees by allowing genetic lineages to merge as well as split. In this paper we present the R package admixturegraph containing tools for building and visualizing admixture graphs, for fitting graph parameters to genetic data, for visualizing goodness...

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Detalles Bibliográficos
Autores principales: Leppälä, Kalle, Nielsen, Svend V, Mailund, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447235/
https://www.ncbi.nlm.nih.gov/pubmed/28158333
http://dx.doi.org/10.1093/bioinformatics/btx048
Descripción
Sumario:SUMMARY: Admixture graphs generalize phylogenetic trees by allowing genetic lineages to merge as well as split. In this paper we present the R package admixturegraph containing tools for building and visualizing admixture graphs, for fitting graph parameters to genetic data, for visualizing goodness of fit and for evaluating the relative goodness of fit between different graphs. AVAILABILITY AND IMPLEMENTATION: GitHub: https://github.com/mailund/admixture_graph and CRAN: https://cran.r-project.org/web/packages/admixturegraph.