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Automated cell type discovery and classification through knowledge transfer

MOTIVATION: Recent advances in mass cytometry allow simultaneous measurements of up to 50 markers at single-cell resolution. However, the high dimensionality of mass cytometry data introduces computational challenges for automated data analysis and hinders translation of new biological understanding...

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Detalles Bibliográficos
Autores principales: Lee, Hao-Chih, Kosoy, Roman, Becker, Christine E, Dudley, Joel T, Kidd, Brian A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447237/
https://www.ncbi.nlm.nih.gov/pubmed/28158442
http://dx.doi.org/10.1093/bioinformatics/btx054