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The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure

Oliguria is one of the clinical hallmarks of renal failure. The broad differential diagnosis is well known, but a rare cause of oliguria is intracranial hypertension (ICH). The actual knowledge to explain this relationship is scarce. Almost all literature is about animals where authors describe the...

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Autores principales: Leyssens, K., Mortelmans, T., Menovsky, T., Abramowicz, D., Twickler, Marcel Th. B., Van Gaal, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447257/
https://www.ncbi.nlm.nih.gov/pubmed/28589048
http://dx.doi.org/10.1155/2017/2582509
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author Leyssens, K.
Mortelmans, T.
Menovsky, T.
Abramowicz, D.
Twickler, Marcel Th. B.
Van Gaal, L.
author_facet Leyssens, K.
Mortelmans, T.
Menovsky, T.
Abramowicz, D.
Twickler, Marcel Th. B.
Van Gaal, L.
author_sort Leyssens, K.
collection PubMed
description Oliguria is one of the clinical hallmarks of renal failure. The broad differential diagnosis is well known, but a rare cause of oliguria is intracranial hypertension (ICH). The actual knowledge to explain this relationship is scarce. Almost all literature is about animals where authors describe the Cushing reflex in response to ICH. We hypothesize that the Cushing reflex is translated towards the sympathetic nervous system and renin-angiotensin-aldosterone system with a subsequent reduction in medullary blood flow and oliguria. Recently, we were confronted with a patient who had complicated pituitary surgery and displayed multiple times an oliguria while he developed ICH.
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spelling pubmed-54472572017-06-06 The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure Leyssens, K. Mortelmans, T. Menovsky, T. Abramowicz, D. Twickler, Marcel Th. B. Van Gaal, L. Case Rep Nephrol Case Report Oliguria is one of the clinical hallmarks of renal failure. The broad differential diagnosis is well known, but a rare cause of oliguria is intracranial hypertension (ICH). The actual knowledge to explain this relationship is scarce. Almost all literature is about animals where authors describe the Cushing reflex in response to ICH. We hypothesize that the Cushing reflex is translated towards the sympathetic nervous system and renin-angiotensin-aldosterone system with a subsequent reduction in medullary blood flow and oliguria. Recently, we were confronted with a patient who had complicated pituitary surgery and displayed multiple times an oliguria while he developed ICH. Hindawi 2017 2017-05-15 /pmc/articles/PMC5447257/ /pubmed/28589048 http://dx.doi.org/10.1155/2017/2582509 Text en Copyright © 2017 K. Leyssens et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Leyssens, K.
Mortelmans, T.
Menovsky, T.
Abramowicz, D.
Twickler, Marcel Th. B.
Van Gaal, L.
The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure
title The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure
title_full The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure
title_fullStr The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure
title_full_unstemmed The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure
title_short The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure
title_sort cushing reflex: oliguria as a reflection of an elevated intracranial pressure
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447257/
https://www.ncbi.nlm.nih.gov/pubmed/28589048
http://dx.doi.org/10.1155/2017/2582509
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