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Toll-Like Receptor 4 in Paraventricular Nucleus Mediates Visceral Hypersensitivity Induced by Maternal Separation
Neonatal maternal separation (MS) is a major early life stress that increases the risk of emotional disorders, visceral pain perception and other brain dysfunction. Elevation of toll-like receptor 4 (TLR4) signaling in the paraventricular nucleus (PVN) precipitates early life colorectal distension (...
Autores principales: | Tang, Hui-Li, Zhang, Gongliang, Ji, Ning-Ning, Du, Lei, Chen, Bin-Bin, Hua, Rong, Zhang, Yong-Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447361/ https://www.ncbi.nlm.nih.gov/pubmed/28611665 http://dx.doi.org/10.3389/fphar.2017.00309 |
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