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The alleviative effects of metformin for lipopolysaccharide-induced acute lung injury rat model and its underlying mechanism
For patients who have sepsis, acute lung injury (ALI) causes most of death. Metformin (Met) is an anti-hyperglycemic agent and it has extensive pharmacological properties. This study aimed to analyze the influence of Met on lipopolysaccharide (LPS) -induced ALI. Met (1, 2, and 4 mg/kg) were injected...
Autores principales: | Zhang, Xiangcheng, Shang, Futai, Hui, Liangliang, Zang, Kui, Sun, Gengyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447443/ https://www.ncbi.nlm.nih.gov/pubmed/28579909 http://dx.doi.org/10.1016/j.jsps.2017.05.001 |
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