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The alleviative effects of metformin for lipopolysaccharide-induced acute lung injury rat model and its underlying mechanism

For patients who have sepsis, acute lung injury (ALI) causes most of death. Metformin (Met) is an anti-hyperglycemic agent and it has extensive pharmacological properties. This study aimed to analyze the influence of Met on lipopolysaccharide (LPS) -induced ALI. Met (1, 2, and 4 mg/kg) were injected...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangcheng, Shang, Futai, Hui, Liangliang, Zang, Kui, Sun, Gengyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447443/
https://www.ncbi.nlm.nih.gov/pubmed/28579909
http://dx.doi.org/10.1016/j.jsps.2017.05.001

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