Effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology induced by the fetal urogenital sinus implants

AIM: The research was to study the effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology. RESULTS: Compared with the model group(MG), Motherwort total alkaloid high, medium dose group(HD, MD) could significantly reduced the p...

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Detalles Bibliográficos
Autores principales: Miao, Mingsan, Tian, Shuo, Bai, Ming, Xiang, Liling, Gao, Jianlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447446/
https://www.ncbi.nlm.nih.gov/pubmed/28579898
http://dx.doi.org/10.1016/j.jsps.2017.04.030
Descripción
Sumario:AIM: The research was to study the effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology. RESULTS: Compared with the model group(MG), Motherwort total alkaloid high, medium dose group(HD, MD) could significantly reduced the pathological changes of the prostate (P < 0.01); Finasteride(FG) and Motherwort total alkaloid low dose group(LD) could significantly reduce the pathological changes of the prostate (P < 0.05); Longbishu capsules(LG), Finasteride, Motherwort total alkaloid medium dose group could significantly reduce the pathological changes of the kidney (P < 0.01); Motherwort total alkaloid low dose group could significantly reduce the pathological changes of the kidney (P < 0.05); Motherwort total alkaloids could improve the pathological changes of the thymus and spleen. CONCLUSION: Motherwort total alkaloid can improve the pathological changes of prostatic hyperplasia in mice.

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