Effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology induced by the fetal urogenital sinus implants

AIM: The research was to study the effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology. RESULTS: Compared with the model group(MG), Motherwort total alkaloid high, medium dose group(HD, MD) could significantly reduced the p...

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Detalles Bibliográficos
Autores principales: Miao, Mingsan, Tian, Shuo, Bai, Ming, Xiang, Liling, Gao, Jianlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447446/
https://www.ncbi.nlm.nih.gov/pubmed/28579898
http://dx.doi.org/10.1016/j.jsps.2017.04.030
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author Miao, Mingsan
Tian, Shuo
Bai, Ming
Xiang, Liling
Gao, Jianlian
author_facet Miao, Mingsan
Tian, Shuo
Bai, Ming
Xiang, Liling
Gao, Jianlian
author_sort Miao, Mingsan
collection PubMed
description AIM: The research was to study the effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology. RESULTS: Compared with the model group(MG), Motherwort total alkaloid high, medium dose group(HD, MD) could significantly reduced the pathological changes of the prostate (P < 0.01); Finasteride(FG) and Motherwort total alkaloid low dose group(LD) could significantly reduce the pathological changes of the prostate (P < 0.05); Longbishu capsules(LG), Finasteride, Motherwort total alkaloid medium dose group could significantly reduce the pathological changes of the kidney (P < 0.01); Motherwort total alkaloid low dose group could significantly reduce the pathological changes of the kidney (P < 0.05); Motherwort total alkaloids could improve the pathological changes of the thymus and spleen. CONCLUSION: Motherwort total alkaloid can improve the pathological changes of prostatic hyperplasia in mice.
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spelling pubmed-54474462017-06-02 Effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology induced by the fetal urogenital sinus implants Miao, Mingsan Tian, Shuo Bai, Ming Xiang, Liling Gao, Jianlian Saudi Pharm J Article AIM: The research was to study the effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology. RESULTS: Compared with the model group(MG), Motherwort total alkaloid high, medium dose group(HD, MD) could significantly reduced the pathological changes of the prostate (P < 0.01); Finasteride(FG) and Motherwort total alkaloid low dose group(LD) could significantly reduce the pathological changes of the prostate (P < 0.05); Longbishu capsules(LG), Finasteride, Motherwort total alkaloid medium dose group could significantly reduce the pathological changes of the kidney (P < 0.01); Motherwort total alkaloid low dose group could significantly reduce the pathological changes of the kidney (P < 0.05); Motherwort total alkaloids could improve the pathological changes of the thymus and spleen. CONCLUSION: Motherwort total alkaloid can improve the pathological changes of prostatic hyperplasia in mice. Elsevier 2017-05 2017-05-07 /pmc/articles/PMC5447446/ /pubmed/28579898 http://dx.doi.org/10.1016/j.jsps.2017.04.030 Text en © 2017 King Saud University http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Miao, Mingsan
Tian, Shuo
Bai, Ming
Xiang, Liling
Gao, Jianlian
Effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology induced by the fetal urogenital sinus implants
title Effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology induced by the fetal urogenital sinus implants
title_full Effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology induced by the fetal urogenital sinus implants
title_fullStr Effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology induced by the fetal urogenital sinus implants
title_full_unstemmed Effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology induced by the fetal urogenital sinus implants
title_short Effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology induced by the fetal urogenital sinus implants
title_sort effect of motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology induced by the fetal urogenital sinus implants
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447446/
https://www.ncbi.nlm.nih.gov/pubmed/28579898
http://dx.doi.org/10.1016/j.jsps.2017.04.030
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