Acute Frontal Lobe Dysfunction Following Prefrontal Low-Frequency Repetitive Transcranial Magnetic Stimulation in a Patient with Treatment-Resistant Depression

The potential of repetitive transcranial magnetic stimulation (rTMS) to treat numerous neurological and psychiatric disorders has been thoroughly studied for the last two decades. Here, we report for the first time, the case of a 65-year-old woman suffering from treatment-resistant depression who de...

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Autores principales: Carle, Guilhem, Touat, Mehdi, Bruno, Nicolas, Galanaud, Damien, Peretti, Charles-Siegfried, Valero-Cabré, Antoni, Levy, Richard, Azuar, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447704/
https://www.ncbi.nlm.nih.gov/pubmed/28611694
http://dx.doi.org/10.3389/fpsyt.2017.00096
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author Carle, Guilhem
Touat, Mehdi
Bruno, Nicolas
Galanaud, Damien
Peretti, Charles-Siegfried
Valero-Cabré, Antoni
Levy, Richard
Azuar, Carole
author_facet Carle, Guilhem
Touat, Mehdi
Bruno, Nicolas
Galanaud, Damien
Peretti, Charles-Siegfried
Valero-Cabré, Antoni
Levy, Richard
Azuar, Carole
author_sort Carle, Guilhem
collection PubMed
description The potential of repetitive transcranial magnetic stimulation (rTMS) to treat numerous neurological and psychiatric disorders has been thoroughly studied for the last two decades. Here, we report for the first time, the case of a 65-year-old woman suffering from treatment-resistant depression who developed an acute frontal lobe syndrome following eight sessions of low-frequency rTMS (LF-rTMS) to the right dorsolateral prefrontal cortex while also treated with sertraline and mianserin. The pathophysiological mechanisms underlying such an unexpected acute frontal lobe dysfunction are discussed in relation to the therapeutic use of LF-rTMS in combination with pharmacotherapy in depressed patients.
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spelling pubmed-54477042017-06-13 Acute Frontal Lobe Dysfunction Following Prefrontal Low-Frequency Repetitive Transcranial Magnetic Stimulation in a Patient with Treatment-Resistant Depression Carle, Guilhem Touat, Mehdi Bruno, Nicolas Galanaud, Damien Peretti, Charles-Siegfried Valero-Cabré, Antoni Levy, Richard Azuar, Carole Front Psychiatry Psychiatry The potential of repetitive transcranial magnetic stimulation (rTMS) to treat numerous neurological and psychiatric disorders has been thoroughly studied for the last two decades. Here, we report for the first time, the case of a 65-year-old woman suffering from treatment-resistant depression who developed an acute frontal lobe syndrome following eight sessions of low-frequency rTMS (LF-rTMS) to the right dorsolateral prefrontal cortex while also treated with sertraline and mianserin. The pathophysiological mechanisms underlying such an unexpected acute frontal lobe dysfunction are discussed in relation to the therapeutic use of LF-rTMS in combination with pharmacotherapy in depressed patients. Frontiers Media S.A. 2017-05-30 /pmc/articles/PMC5447704/ /pubmed/28611694 http://dx.doi.org/10.3389/fpsyt.2017.00096 Text en Copyright © 2017 Carle, Touat, Bruno, Galanaud, Peretti, Valero-Cabré, Levy and Azuar. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Carle, Guilhem
Touat, Mehdi
Bruno, Nicolas
Galanaud, Damien
Peretti, Charles-Siegfried
Valero-Cabré, Antoni
Levy, Richard
Azuar, Carole
Acute Frontal Lobe Dysfunction Following Prefrontal Low-Frequency Repetitive Transcranial Magnetic Stimulation in a Patient with Treatment-Resistant Depression
title Acute Frontal Lobe Dysfunction Following Prefrontal Low-Frequency Repetitive Transcranial Magnetic Stimulation in a Patient with Treatment-Resistant Depression
title_full Acute Frontal Lobe Dysfunction Following Prefrontal Low-Frequency Repetitive Transcranial Magnetic Stimulation in a Patient with Treatment-Resistant Depression
title_fullStr Acute Frontal Lobe Dysfunction Following Prefrontal Low-Frequency Repetitive Transcranial Magnetic Stimulation in a Patient with Treatment-Resistant Depression
title_full_unstemmed Acute Frontal Lobe Dysfunction Following Prefrontal Low-Frequency Repetitive Transcranial Magnetic Stimulation in a Patient with Treatment-Resistant Depression
title_short Acute Frontal Lobe Dysfunction Following Prefrontal Low-Frequency Repetitive Transcranial Magnetic Stimulation in a Patient with Treatment-Resistant Depression
title_sort acute frontal lobe dysfunction following prefrontal low-frequency repetitive transcranial magnetic stimulation in a patient with treatment-resistant depression
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447704/
https://www.ncbi.nlm.nih.gov/pubmed/28611694
http://dx.doi.org/10.3389/fpsyt.2017.00096
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