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Reversing EGFR Mediated Immunoescape by Targeted Monoclonal Antibody Therapy
Uncontrolled growth is a signature of carcinogenesis, in part mediated by overexpression or overstimulation of growth factor receptors. The epidermal growth factor receptor (EGFR) mediates activation of multiple oncogenic signaling pathways and escape from recognition by the host immune system. We d...
Autores principales: | Concha-Benavente, Fernando, Ferris, Robert L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447743/ https://www.ncbi.nlm.nih.gov/pubmed/28611673 http://dx.doi.org/10.3389/fphar.2017.00332 |
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