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Autophagy and Its Impact on Neurodegenerative Diseases: New Roles for TDP-43 and C9orf72

Autophagy is a catabolic mechanism where intracellular material is degraded by vesicular structures called autophagolysosomes. Autophagy is necessary to maintain the normal function of the central nervous system (CNS), avoiding the accumulation of misfolded and aggregated proteins. Consistently, imp...

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Detalles Bibliográficos
Autores principales:	Budini, Mauricio, Buratti, Emanuele, Morselli, Eugenia, Criollo, Alfredo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447761/ https://www.ncbi.nlm.nih.gov/pubmed/28611593 http://dx.doi.org/10.3389/fnmol.2017.00170

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