Pathobiological implications of the d16HER2 splice variant for stemness and aggressiveness of HER2-positive breast cancer

We have previously shown that the d16HER2 splice variant is linked to HER2-positive breast cancer (BC) tumorigenesis, progression and response to Trastuzumab. However, the mechanisms by which d16HER2 contributes to HER2-driven aggressiveness and targeted therapy susceptibility remain uncertain. Here...

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Detalles Bibliográficos
Autores principales: Castagnoli, L, Ghedini, G C, Koschorke, A, Triulzi, T, Dugo, M, Gasparini, P, Casalini, P, Palladini, A, Iezzi, M, Lamolinara, A, Lollini, P L, Nanni, P, Chiodoni, C, Tagliabue, E, Pupa, S M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447867/
https://www.ncbi.nlm.nih.gov/pubmed/27641338
http://dx.doi.org/10.1038/onc.2016.338

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