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The Human Immunodeficiency Virus Continuum of Care in European Union Countries in 2013: Data and Challenges

BACKGROUND. The Joint United Nations Programme on HIV/AIDS (UNAIDS) has set a “90-90-90” target to curb the human immunodeficiency virus (HIV) epidemic by 2020, but methods used to assess whether countries have reached this target are not standardized, hindering comparisons. METHODS. Through a colla...

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Autores principales: Gourlay, Annabelle, Noori, Teymur, Pharris, Anastasia, Axelsson, Maria, Costagliola, Dominique, Cowan, Susan, Croxford, Sara, d’Arminio Monforte, Antonella, del Amo, Julia, Delpech, Valerie, Díaz, Asunción, Girardi, Enrico, Gunsenheimer-Bartmeyer, Barbara, Hernando, Victoria, Jose, Sophie, Leierer, Gisela, Nikolopoulos, Georgios, Obel, Niels, Op de Coul, Eline, Paraskeva, Dimitra, Reiss, Peter, Sabin, Caroline, Sasse, André, Schmid, Daniela, Sonnerborg, Anders, Spina, Alexander, Suligoi, Barbara, Supervie, Virginie, Touloumi, Giota, Van Beckhoven, Dominique, van Sighem, Ard, Vourli, Georgia, Zangerle, Robert, Porter, Kholoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447871/
https://www.ncbi.nlm.nih.gov/pubmed/28369283
http://dx.doi.org/10.1093/cid/cix212
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author Gourlay, Annabelle
Noori, Teymur
Pharris, Anastasia
Axelsson, Maria
Costagliola, Dominique
Cowan, Susan
Croxford, Sara
d’Arminio Monforte, Antonella
del Amo, Julia
Delpech, Valerie
Díaz, Asunción
Girardi, Enrico
Gunsenheimer-Bartmeyer, Barbara
Hernando, Victoria
Jose, Sophie
Leierer, Gisela
Nikolopoulos, Georgios
Obel, Niels
Op de Coul, Eline
Paraskeva, Dimitra
Reiss, Peter
Sabin, Caroline
Sasse, André
Schmid, Daniela
Sonnerborg, Anders
Spina, Alexander
Suligoi, Barbara
Supervie, Virginie
Touloumi, Giota
Van Beckhoven, Dominique
van Sighem, Ard
Vourli, Georgia
Zangerle, Robert
Porter, Kholoud
author_facet Gourlay, Annabelle
Noori, Teymur
Pharris, Anastasia
Axelsson, Maria
Costagliola, Dominique
Cowan, Susan
Croxford, Sara
d’Arminio Monforte, Antonella
del Amo, Julia
Delpech, Valerie
Díaz, Asunción
Girardi, Enrico
Gunsenheimer-Bartmeyer, Barbara
Hernando, Victoria
Jose, Sophie
Leierer, Gisela
Nikolopoulos, Georgios
Obel, Niels
Op de Coul, Eline
Paraskeva, Dimitra
Reiss, Peter
Sabin, Caroline
Sasse, André
Schmid, Daniela
Sonnerborg, Anders
Spina, Alexander
Suligoi, Barbara
Supervie, Virginie
Touloumi, Giota
Van Beckhoven, Dominique
van Sighem, Ard
Vourli, Georgia
Zangerle, Robert
Porter, Kholoud
author_sort Gourlay, Annabelle
collection PubMed
description BACKGROUND. The Joint United Nations Programme on HIV/AIDS (UNAIDS) has set a “90-90-90” target to curb the human immunodeficiency virus (HIV) epidemic by 2020, but methods used to assess whether countries have reached this target are not standardized, hindering comparisons. METHODS. Through a collaboration formed by the European Centre for Disease Prevention and Control (ECDC) with European HIV cohorts and surveillance agencies, we constructed a standardized, 4-stage continuum of HIV care for 11 European Union countries for 2013. Stages were defined as (1) number of people living with HIV in the country by end of 2013; (2) proportion of stage 1 ever diagnosed; (3) proportion of stage 2 that ever initiated ART; and (4) proportion of stage 3 who became virally suppressed (≤200 copies/mL). Case surveillance data were used primarily to derive stages 1 (using back-calculation models) and 2, and cohort data for stages 3 and 4. RESULTS. In 2013, 674500 people in the 11 countries were estimated to be living with HIV, ranging from 5500 to 153400 in each country. Overall HIV prevalence was 0.22% (range, 0.09%–0.36%). Overall proportions of each previous stage were 84% diagnosed, 84% on ART, and 85% virally suppressed (60% of people living with HIV). Two countries achieved ≥90% for all stages, and more than half had reached ≥90% for at least 1 stage. CONCLUSIONS. European Union countries are nearing the 90-90-90 target. Reducing the proportion undiagnosed remains the greatest barrier to achieving this target, suggesting that further efforts are needed to improve HIV testing rates. Standardizing methods to derive comparable continuums of care remains a challenge.
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spelling pubmed-54478712017-06-02 The Human Immunodeficiency Virus Continuum of Care in European Union Countries in 2013: Data and Challenges Gourlay, Annabelle Noori, Teymur Pharris, Anastasia Axelsson, Maria Costagliola, Dominique Cowan, Susan Croxford, Sara d’Arminio Monforte, Antonella del Amo, Julia Delpech, Valerie Díaz, Asunción Girardi, Enrico Gunsenheimer-Bartmeyer, Barbara Hernando, Victoria Jose, Sophie Leierer, Gisela Nikolopoulos, Georgios Obel, Niels Op de Coul, Eline Paraskeva, Dimitra Reiss, Peter Sabin, Caroline Sasse, André Schmid, Daniela Sonnerborg, Anders Spina, Alexander Suligoi, Barbara Supervie, Virginie Touloumi, Giota Van Beckhoven, Dominique van Sighem, Ard Vourli, Georgia Zangerle, Robert Porter, Kholoud Clin Infect Dis Major Article BACKGROUND. The Joint United Nations Programme on HIV/AIDS (UNAIDS) has set a “90-90-90” target to curb the human immunodeficiency virus (HIV) epidemic by 2020, but methods used to assess whether countries have reached this target are not standardized, hindering comparisons. METHODS. Through a collaboration formed by the European Centre for Disease Prevention and Control (ECDC) with European HIV cohorts and surveillance agencies, we constructed a standardized, 4-stage continuum of HIV care for 11 European Union countries for 2013. Stages were defined as (1) number of people living with HIV in the country by end of 2013; (2) proportion of stage 1 ever diagnosed; (3) proportion of stage 2 that ever initiated ART; and (4) proportion of stage 3 who became virally suppressed (≤200 copies/mL). Case surveillance data were used primarily to derive stages 1 (using back-calculation models) and 2, and cohort data for stages 3 and 4. RESULTS. In 2013, 674500 people in the 11 countries were estimated to be living with HIV, ranging from 5500 to 153400 in each country. Overall HIV prevalence was 0.22% (range, 0.09%–0.36%). Overall proportions of each previous stage were 84% diagnosed, 84% on ART, and 85% virally suppressed (60% of people living with HIV). Two countries achieved ≥90% for all stages, and more than half had reached ≥90% for at least 1 stage. CONCLUSIONS. European Union countries are nearing the 90-90-90 target. Reducing the proportion undiagnosed remains the greatest barrier to achieving this target, suggesting that further efforts are needed to improve HIV testing rates. Standardizing methods to derive comparable continuums of care remains a challenge. Oxford University Press 2017-06-15 2017-03-20 /pmc/articles/PMC5447871/ /pubmed/28369283 http://dx.doi.org/10.1093/cid/cix212 Text en © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Major Article
Gourlay, Annabelle
Noori, Teymur
Pharris, Anastasia
Axelsson, Maria
Costagliola, Dominique
Cowan, Susan
Croxford, Sara
d’Arminio Monforte, Antonella
del Amo, Julia
Delpech, Valerie
Díaz, Asunción
Girardi, Enrico
Gunsenheimer-Bartmeyer, Barbara
Hernando, Victoria
Jose, Sophie
Leierer, Gisela
Nikolopoulos, Georgios
Obel, Niels
Op de Coul, Eline
Paraskeva, Dimitra
Reiss, Peter
Sabin, Caroline
Sasse, André
Schmid, Daniela
Sonnerborg, Anders
Spina, Alexander
Suligoi, Barbara
Supervie, Virginie
Touloumi, Giota
Van Beckhoven, Dominique
van Sighem, Ard
Vourli, Georgia
Zangerle, Robert
Porter, Kholoud
The Human Immunodeficiency Virus Continuum of Care in European Union Countries in 2013: Data and Challenges
title The Human Immunodeficiency Virus Continuum of Care in European Union Countries in 2013: Data and Challenges
title_full The Human Immunodeficiency Virus Continuum of Care in European Union Countries in 2013: Data and Challenges
title_fullStr The Human Immunodeficiency Virus Continuum of Care in European Union Countries in 2013: Data and Challenges
title_full_unstemmed The Human Immunodeficiency Virus Continuum of Care in European Union Countries in 2013: Data and Challenges
title_short The Human Immunodeficiency Virus Continuum of Care in European Union Countries in 2013: Data and Challenges
title_sort human immunodeficiency virus continuum of care in european union countries in 2013: data and challenges
topic Major Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447871/
https://www.ncbi.nlm.nih.gov/pubmed/28369283
http://dx.doi.org/10.1093/cid/cix212
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