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Effects of expressing human T-cell leukemia virus type 1 (HTLV-I) oncoprotein Tax on DOK1, DOK2 and DOK3 gene expression in mice
Transgenic mice expressing the tax gene from human T-cell leukemia virus type 1 (HTLV-I) genome developed T-cell leukemia or histiocytic sarcoma after at least 12 months. The transgenic mice showed low expression of the downstream of tyrosine kinase (DOK) family members, DOK1, DOK2 and DOK3, which w...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Japanese Society of Veterinary Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447985/ https://www.ncbi.nlm.nih.gov/pubmed/28302940 http://dx.doi.org/10.1292/jvms.17-0034 |