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Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses
In this study, the virucidal effect of a novel electrically charged disinfectant CAC-717 was investigated. CAC-717 is produced by applying an electric field to mineral water containing calcium hydrogen carbonate to generate mesoscopic crystals. Virus titration analysis showed a >3 log reduction o...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Veterinary Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447986/ https://www.ncbi.nlm.nih.gov/pubmed/28392537 http://dx.doi.org/10.1292/jvms.16-0603 |
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author | NAKASHIMA, Ryuji KAWAMOTO, Masaomi MIYAZAKI, Shigeru ONISHI, Rumiko FURUSAKI, Koichi OSAKI, Maho KIRISAWA, Rikio SAKUDO, Akikazu ONODERA, Takashi |
author_facet | NAKASHIMA, Ryuji KAWAMOTO, Masaomi MIYAZAKI, Shigeru ONISHI, Rumiko FURUSAKI, Koichi OSAKI, Maho KIRISAWA, Rikio SAKUDO, Akikazu ONODERA, Takashi |
author_sort | NAKASHIMA, Ryuji |
collection | PubMed |
description | In this study, the virucidal effect of a novel electrically charged disinfectant CAC-717 was investigated. CAC-717 is produced by applying an electric field to mineral water containing calcium hydrogen carbonate to generate mesoscopic crystals. Virus titration analysis showed a >3 log reduction of influenza A viruses after treatment with CAC-717 for 1 min in room temperature, while infectivity was undetectable after 15 min treatment. Adding bovine serum albumin to CAC-717 solution did not affect the disinfectant effect. Although CAC-717 is an alkaline solution (pH=12.39), upon contact with human tissue, its pH becomes almost physiological (pH 8.84) after accelerated electric discharge, which enables its use against influenza viruses. Therefore, CAC-717 may be used as a preventative measure against influenza A viruses and for biosecurity in the environment. |
format | Online Article Text |
id | pubmed-5447986 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The Japanese Society of Veterinary Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-54479862017-06-01 Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses NAKASHIMA, Ryuji KAWAMOTO, Masaomi MIYAZAKI, Shigeru ONISHI, Rumiko FURUSAKI, Koichi OSAKI, Maho KIRISAWA, Rikio SAKUDO, Akikazu ONODERA, Takashi J Vet Med Sci Virology In this study, the virucidal effect of a novel electrically charged disinfectant CAC-717 was investigated. CAC-717 is produced by applying an electric field to mineral water containing calcium hydrogen carbonate to generate mesoscopic crystals. Virus titration analysis showed a >3 log reduction of influenza A viruses after treatment with CAC-717 for 1 min in room temperature, while infectivity was undetectable after 15 min treatment. Adding bovine serum albumin to CAC-717 solution did not affect the disinfectant effect. Although CAC-717 is an alkaline solution (pH=12.39), upon contact with human tissue, its pH becomes almost physiological (pH 8.84) after accelerated electric discharge, which enables its use against influenza viruses. Therefore, CAC-717 may be used as a preventative measure against influenza A viruses and for biosecurity in the environment. The Japanese Society of Veterinary Science 2017-04-10 2017-05 /pmc/articles/PMC5447986/ /pubmed/28392537 http://dx.doi.org/10.1292/jvms.16-0603 Text en ©2017 The Japanese Society of Veterinary Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Virology NAKASHIMA, Ryuji KAWAMOTO, Masaomi MIYAZAKI, Shigeru ONISHI, Rumiko FURUSAKI, Koichi OSAKI, Maho KIRISAWA, Rikio SAKUDO, Akikazu ONODERA, Takashi Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses |
title | Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses |
title_full | Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses |
title_fullStr | Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses |
title_full_unstemmed | Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses |
title_short | Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses |
title_sort | evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza a viruses |
topic | Virology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447986/ https://www.ncbi.nlm.nih.gov/pubmed/28392537 http://dx.doi.org/10.1292/jvms.16-0603 |
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