Cargando…
The Crucial Role of DNA Methylation and MeCP2 in Neuronal Function
A neuron is unique in its ability to dynamically modify its transcriptional output in response to synaptic activity while maintaining a core gene expression program that preserves cellular identity throughout a lifetime that is longer than almost every other cell type in the body. A contributing fac...
Autores principales: | Fasolino, Maria, Zhou, Zhaolan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448015/ https://www.ncbi.nlm.nih.gov/pubmed/28505093 http://dx.doi.org/10.3390/genes8050141 |
Ejemplares similares
-
Genetic Modifiers of MeCP2 Function in Drosophila
por: Cukier, Holly N., et al.
Publicado: (2008) -
Role of MeCP2, DNA methylation, and HDACs in regulating synapse function
por: Kavalali, Ege T., et al.
Publicado: (2011) -
The methyl-CpG-binding domain (MBD) is crucial for MeCP2’s dysfunction-induced defects in adult newborn neurons
por: Zhao, Na, et al.
Publicado: (2015) -
Neuronal non-CG methylation is an essential target for MeCP2 function
por: Tillotson, Rebekah, et al.
Publicado: (2021) -
Differential dynamics specify MeCP2 function at methylated DNA and nucleosomes
por: Chua, Gabriella N. L., et al.
Publicado: (2023)