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MYC—Master Regulator of the Cancer Epigenome and Transcriptome

Overexpression of MYC is a hallmark of many human cancers. The MYC oncogene has long been thought to execute its neoplastic functions by acting as a classic transcription factor, deregulating the expression of a large number of specific target genes. However, MYC’s influence on many of these target...

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Detalles Bibliográficos
Autores principales: Poole, Candace J., van Riggelen, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448016/
https://www.ncbi.nlm.nih.gov/pubmed/28505071
http://dx.doi.org/10.3390/genes8050142