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The Clinical Course of Patients with Preschool Manifestation of Type 1 Diabetes Is Independent of the HLA DR-DQ Genotype

Introduction: Major histocompatibility complex class II genes are considered major genetic risk factors for autoimmune diabetes. We analysed Human Leukocyte Antigen (HLA) DR and DQ haplotypes in a cohort with early-onset (age < 5 years), long term type 1 diabetes (T1D) and explored their influenc...

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Detalles Bibliográficos
Autores principales: Reinauer, Christina, Rosenbauer, Joachim, Bächle, Christina, Herder, Christian, Roden, Michael, Ellard, Sian, De Franco, Elisa, Karges, Beate, Holl, Reinhard W., Enczmann, Jürgen, Meissner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448020/
https://www.ncbi.nlm.nih.gov/pubmed/28534863
http://dx.doi.org/10.3390/genes8050146