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Coexistence of KRAS and BRAF Mutations in Colorectal Cancer: A Case Report Supporting The Concept of Tumoral Heterogeneity
The detection of KRAS and BRAF mutations is a crucial step for the correct therapeutic approach and predicting the epidermal growth factor receptor (EGFR)-targeted therapy resistance of colorectal carcinomas. The concomitant KRAS and BRAF mutations occur rarely in the colorectal cancers (CRCs) with...
Autores principales: | Larki, Pegah, Gharib, Ehsan, Yaghoob Taleghani, Mohammad, Khorshidi, Fatemeh, Nazemalhosseini-Mojarad, Ehsan, Asadzadeh Aghdaei, Hamid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royan Institute
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448326/ https://www.ncbi.nlm.nih.gov/pubmed/28580315 http://dx.doi.org/10.22074/cellj.2017.5123 |
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