Combined oral administration of L-arginine and tetrahydrobiopterin in a rat model of pulmonary arterial hypertension

Alterations in the nitric oxide (NO) pathway play a major role in pulmonary arterial hypertension (PAH). L-arginine (LA) and tetrahydrobiopterin (BH(4)) are main substrates in the production of NO, which mediates pulmonary vasodilation. Administration of either LA or BH(4) decrease pulmonary artery...

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Detalles Bibliográficos
Autores principales: Schreiber, C., Eilenberg, M.S., Panzenboeck, A., Winter, M.P., Bergmeister, H., Herzog, R., Mascherbauer, J., Lang, I.M., Bonderman, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448548/
https://www.ncbi.nlm.nih.gov/pubmed/28680568
http://dx.doi.org/10.1086/689289

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