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PI(3,4)P(2) plays critical roles in the regulation of focal adhesion dynamics of MDA‐MB‐231 breast cancer cells

Phosphoinositides play pivotal roles in the regulation of cancer cell phenotypes. Among them, phosphatidylinositol 3,4‐bisphosphate (PI(3,4)P(2)) localizes to the invadopodia, and positively regulates tumor cell invasion. In this study, we examined the effect of PI(3,4)P(2) on focal adhesion dynamic...

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Detalles Bibliográficos
Autores principales: Fukumoto, Miki, Ijuin, Takeshi, Takenawa, Tadaomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448597/
https://www.ncbi.nlm.nih.gov/pubmed/28247964
http://dx.doi.org/10.1111/cas.13215